Dr. Andreas Marzinzik

Dr. Andreas Marzinzik is Director in the Hit Generation Science department at the Novartis Institutes for BioMedical Research. Andreas studied chemistry at Bochum University and received a Ph.D. in organic chemistry from Essen University. He joined Novartis in 1995 and served various roles within research until 1999, where he joined Prof. K. B. Sharpless’ group at the Scripps Research Institute in La Jolla for a year-long sabbatical. Andreas was appointed head of the Integrated Combinatorial Lead Discovery program in 2000. He was awarded the Novartis Leading Scientist award in 2005. His research expanded from combinatorial library methodologies and screening to new hit finding technologies for difficult targets and alternative inhibitory approaches for kinases. After initiating antibody drug conjugates chemistry and implementing peptide therapeutic group at Novartis, he moved to his present position as Director in Hit Generation Science. Andreas’ research is concerned with Medicinal Chemistry for protein-protein interactions, lead generation chemistry, library science, and recently he also took the chemistry lead regarding the implementation of DNA encoded chemistry and ribosomal synthesis of macrocyclic peptides.